DYNC1H1 antibody (Internal Region)

Catalog No. ABIN6261391

Product Details anti-DYNC1H1 Antibody

Target: DYNC1H1 (Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYNC1H1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: DYNC1H1 Antibody detects endogenous levels of total DYNC1H1.

Predicted Reactivity: Pig,Bovine,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DYNC1H1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DYNC1H1

Target: DYNC1H1 (Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1))

Alternative Name: DYNC1H1 (DYNC1H1 Products)

Background:

Description: Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity, the force-producing power stroke is thought to occur on release of ADP. Plays a role in mitotic spindle assembly and metaphase plate congression (PubMed:27462074).

Gene: DYNC1H1

Molecular Weight: 532kDa

Gene ID: 1778

UniProt: Q14204

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization