Dystonin antibody (C-Term)

Catalog No. ABIN6261376

Product Details anti-Dystonin Antibody

Target: Dystonin (DST)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dystonin antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: DST Antibody detects endogenous levels of total DST.

Predicted Reactivity: Pig,Bovine,Horse,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human DST, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Dystonin

Target: Dystonin (DST)

Alternative Name: DST (DST Products)

Synonyms: DST antibody, BPAG1 antibody, BP240 antibody, BPA antibody, CATX-15 antibody, CATX15 antibody, D6S1101 antibody, DMH antibody, DT antibody, HSAN6 antibody, MACF2 antibody, DKFZp469H1318 antibody, bpag1 antibody, fc38a05 antibody, wu:fc38a05 antibody, dst antibody, 2310001O04Rik antibody, A830042E19Rik antibody, AW554249 antibody, BP230 antibody, BPAG1-n antibody, Bpag antibody, Bpag1 antibody, Macf2 antibody, ah antibody, athetoid antibody, dt antibody, mKIAA0728 antibody, nmf203 antibody, nmf339 antibody, dystonin antibody, dystonin L homeolog antibody, putative bullous pemphigoid antigen 1 antibody, LOC100056885 antibody, DST antibody, LOC535297 antibody, Dst antibody, dst antibody, dst.L antibody, Smp_159110 antibody, LOC100092576 antibody

Background:

Description: Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Mediates docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport through its interaction with TMEM108 and DCTN1 (By similarity).

Gene: DST

Molecular Weight: 861kDa

Gene ID: 667

UniProt: Q03001