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POLL antibody (C-Term)

POLL Reactivity: Human, Rat, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261322
  • Target See all POLL Antibodies
    POLL (Polymerase (DNA Directed), lambda (POLL))
    Binding Specificity
    • 15
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 31
    • 22
    • 17
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 45
    • 1
    Rabbit
    Clonality
    • 46
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLL antibody is un-conjugated
    Application
    • 32
    • 14
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    DNA pol lambda Antibody detects endogenous levels of total DNA pol lambda.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human DNA pol lambda, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product POLL Primary Antibody
  • Application Notes
    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    POLL (Polymerase (DNA Directed), lambda (POLL))
    Alternative Name
    POLL (POLL Products)
    Synonyms
    T10O24.13 antibody, T10O24_13 antibody, zgc:66320 antibody, zgc:77901 antibody, wu:fe49a04 antibody, beta-n antibody, pol-kappa antibody, BETAN antibody, POLKAPPA antibody, 1110003P06Rik antibody, AV007317 antibody, DNA polymerase lambda (POLL) antibody, DNA polymerase lambda antibody, polymerase (DNA directed), lambda antibody, polymerase (DNA) lambda antibody, Pol{lambda} antibody, PTRG_00468 antibody, poll antibody, POLL antibody, MCYG_03796 antibody, LOC9325878 antibody, MGYG_02138 antibody, Poll antibody
    Background

    Description: DNA polymerase that functions in several pathways of DNA repair (PubMed:11457865, PubMed:19806195, PubMed:20693240). Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA (PubMed:11457865, PubMed:19806195). Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination (PubMed:19806195, PubMed:20693240). Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities (PubMed:10982892, PubMed:10887191, PubMed:12809503, PubMed:14627824, PubMed:15537631, PubMed:19806195). Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity (PubMed:11457865, PubMed:19806195).

    Gene: POLL

    Molecular Weight
    63kDa
    Gene ID
    27343
    UniProt
    Q9UGP5
    Pathways
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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