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Dihydrofolate Reductase antibody

DHFR Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261285
  • Target See all Dihydrofolate Reductase (DHFR) Antibodies
    Dihydrofolate Reductase (DHFR)
    Reactivity
    • 34
    • 19
    • 16
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 28
    • 9
    • 1
    Rabbit
    Clonality
    • 28
    • 10
    Polyclonal
    Conjugate
    • 27
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Dihydrofolate Reductase antibody is un-conjugated
    Application
    • 25
    • 13
    • 11
    • 10
    • 8
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    DHFR Antibody detects endogenous levels of total DHFR
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human DHFR
    Isotype
    IgG
    Top Product
    Discover our top product DHFR Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    Dihydrofolate Reductase (DHFR)
    Alternative Name
    DHFR (DHFR Products)
    Synonyms
    DHFR antibody, F10_orf160 antibody, ECK0049 antibody, JW0047 antibody, tmrA antibody, cb595 antibody, zgc:86637 antibody, DDBDRAFT_0187132 antibody, DDBDRAFT_0230113 antibody, DDB_0187132 antibody, DDB_0230113 antibody, CG14887 antibody, Dmel\\CG14887 antibody, dhfr antibody, DHFRP1 antibody, DYR antibody, 8430436I03Rik antibody, AA607882 antibody, AI662710 antibody, AW555094 antibody, Dhfr1 antibody, confers resistance to sulfonamides antibody, dihydrofolate reductase antibody, dihydrofolate reductase DhfR antibody, Dihydrofolate reductase antibody, dhfr antibody, DHFR antibody, dhfR antibody, folA antibody, dfrA antibody, LOC707382 antibody, CNJ01940 antibody, DDB_G0286755 antibody, Dhfr antibody, Mesil_0096 antibody, Arch_0408 antibody, Fbal_3367 antibody, Ilyop_0482 antibody, Lbys_2007 antibody, Riean_0733 antibody, Mrub_1855 antibody, Poras_0766 antibody, Halhy_3552 antibody, Mesop_3614 antibody, LOC609048 antibody
    Background

    Description: Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2.

    Gene: DHFR

    Molecular Weight
    21kDa
    Gene ID
    1719
    UniProt
    P00374
    Pathways
    Mitotic G1-G1/S Phases
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