beta Defensin 1 antibody (Internal Region)
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- Target See all beta Defensin 1 (DEFB1) Antibodies
- beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This beta Defensin 1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- Defensin beta-1 Antibody detects endogenous levels of total Defensin beta-1.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Defensin beta-1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product DEFB1 Primary Antibody
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- Application Notes
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))
- Alternative Name
- DEFB1 (DEFB1 Products)
- Synonyms
- BD1 antibody, DEFB-1 antibody, DEFB101 antibody, HBD1 antibody, AW260221 antibody, BD-1 antibody, DEFB1-like antibody, RHBD-1 antibody, CBD1 antibody, PBD-1 antibody, DEFB1 antibody, BNBD-1 antibody, defensin beta 1 antibody, avian beta-defensin 1 antibody, defensin, beta 1 antibody, beta-defensin 1-like antibody, beta-defensin 1 antibody, DEFB1 antibody, Defb1 antibody, AvBD1 antibody, LOC100861170 antibody
- Background
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Description: Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636).
Gene: DEFB1
- Molecular Weight
- 7 kDa
- Gene ID
- 1672
- UniProt
- P60022
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