DEFa3 antibody (Internal Region)

Catalog No. ABIN6261264

Product Details anti-DEFa3 Antibody

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEFa3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: Defensin alpha3 Antibody detects endogenous levels of total Defensin alpha3.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Defensin alpha3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DEFa3

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Alternative Name: DEFA3 (DEFa3 Products)

Synonyms: Defa27 antibody, Defcr-3 antibody, Defcr3 antibody, DEF3 antibody, HNP-3 antibody, HNP3 antibody, HP-3 antibody, HP3 antibody, defensin, alpha 3, neutrophil-specific antibody, defensin, alpha, 3 antibody, defensin alpha 3 antibody, DEFA3 antibody, Defa3 antibody

Background:

Description: Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Gene: DEFA3

Molecular Weight: 10 kDa

Gene ID: 1668

UniProt: P59666

Pathways: Cellular Response to Molecule of Bacterial Origin