alpha Defensin 1 antibody

Catalog No. ABIN6261263

Product Details anti-alpha Defensin 1 Antibody

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Defensin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: Defensin alpha1 Antibody detects endogenous levels of total Defensin alpha1

Cross-Reactivity: Human, Mouse (Murine)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Defensin alpha1

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000 IHC 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for alpha Defensin 1

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Alternative Name: Defensin alpha1 (DEFA1 Products)

Synonyms: DEF1 antibody, DEFA2 antibody, HNP-1 antibody, HP-1 antibody, HP1 antibody, MRS antibody, Defcr antibody, Defcr1 antibody, DEFA1 antibody, Defa antibody, Def antibody, GB19392 antibody, defensin alpha 1 antibody, defensin, alpha 1 antibody, defensin alpha 5 antibody, alpha-defensin 1A antibody, defensin 1 antibody, neutrophil defensin 1 antibody, DEFA1 antibody, Defa1 antibody, Defa5 antibody, MNP1A antibody, Def1 antibody, LOC107973256 antibody

Background:

Description: Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Gene: DEFA1, DEFA1B

Molecular Weight: 10 kDa

Gene ID: 1, 667, 728

UniProt: P59665

Pathways: Cellular Response to Molecule of Bacterial Origin