Cyclin L1 antibody (C-Term)

Catalog No. ABIN6261157

Product Details anti-Cyclin L1 Antibody

Target: Cyclin L1 (CCNL1)

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Cyclin L1 Antibody detects endogenous levels of total Cyclin L1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cyclin L1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Cyclin L1

Target: Cyclin L1 (CCNL1)

Alternative Name: CCNL1 (CCNL1 Products)

Synonyms: ANIA6A antibody, PRO1073 antibody, ania-6a antibody, 2610030E23Rik antibody, AU018493 antibody, Ccnl antibody, Ania-6a antibody, ccnl1 antibody, fd99b09 antibody, wu:fd99b09 antibody, zgc:55544 antibody, MCM2 antibody, cyclin-L1 antibody, MGC132032 antibody, bm-001 antibody, pro1073 antibody, MGC108436 antibody, Ccnl1 antibody, cyclin L1 antibody, cyclin L1b antibody, cyclin-L1 antibody, cyclin L1 L homeolog antibody, cyclin L1 S homeolog antibody, CCNL1 antibody, Ccnl1 antibody, ccnl1b antibody, LOC485730 antibody, ccnl1.L antibody, ccnl1 antibody, LOC100136245 antibody, ccnl1.S antibody

Background:

Description: Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs) (PubMed:18216018). Inhibited by the CDK-specific inhibitor CDKN1A/p21 (PubMed:11980906). May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) (PubMed:12414649, PubMed:15700036).

Gene: CCNL1

Molecular Weight: 60kDa

Gene ID: 57018

UniProt: Q9UK58