CUX1 antibody (N-Term)

Catalog No. ABIN6261116

Product Details anti-CUX1 Antibody

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: CUTL1 Antibody detects endogenous levels of total CUTL1.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CUTL1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CUX1

Target: CUX1 (Cut-Like Homeobox 1 (CUX1))

Alternative Name: CUX1 (CUX1 Products)

Background:

Description: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor, binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer, may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity).

Gene: CUX1

Molecular Weight: 164 kDa

Gene ID: 1523

UniProt: P39880

Pathways: Cellular Glucan Metabolic Process