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Complexin 1 antibody (N-Term)

CPLX1 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261003
  • Target See all Complexin 1 (CPLX1) Antibodies
    Complexin 1 (CPLX1)
    Binding Specificity
    • 15
    • 14
    • 8
    • 7
    • 6
    • 6
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 49
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 52
    Polyclonal
    Conjugate
    • 14
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Complexin 1 antibody is un-conjugated
    Application
    • 36
    • 22
    • 19
    • 13
    • 13
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    CPLX1 Antibody detects endogenous levels of total CPLX1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CPLX1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CPLX1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    Complexin 1 (CPLX1)
    Alternative Name
    CPLX1 (CPLX1 Products)
    Synonyms
    MGC84299 antibody, CPLX1 antibody, CPX-I antibody, CPX1 antibody, 921-S antibody, complexin 1 L homeolog antibody, complexin 1 antibody, cplx1.L antibody, CPLX1 antibody, cplx1 antibody, Cplx1 antibody
    Background

    Description: Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles (PubMed:21785414). Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse (PubMed:21785414). Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.

    Gene: CPLX1

    Molecular Weight
    15-20 kDa
    Gene ID
    10815
    UniProt
    O14810
    Pathways
    Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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