CNOT10 antibody (Internal Region)

Catalog No. ABIN6260913

Product Details anti-CNOT10 Antibody

Target: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: CNOT10 Antibody detects endogenous levels of total CNOT10.

Predicted Reactivity: Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CNOT10, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CNOT10

Target: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Alternative Name: CNOT10 (CNOT10 Products)

Synonyms: 2600001P13Rik antibody, cnot10 antibody, im:7139356 antibody, zgc:152939 antibody, cnot10-a antibody, cnot10-b antibody, CCR4-NOT transcription complex subunit 10 antibody, CCR4-NOT transcription complex, subunit 10 antibody, CCR4-NOT transcription complex subunit 10 S homeolog antibody, CCR4-NOT transcription complex subunit 10 L homeolog antibody, CNOT10 antibody, Cnot10 antibody, cnot10.S antibody, cnot10 antibody, cnot10.L antibody

Background:

Description: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex.

Gene: CNOT10

Molecular Weight: 82 kDa

Gene ID: 25904

UniProt: Q9H9A5