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CNGA3 antibody (N-Term)

CNGA3 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6260908
  • Target See all CNGA3 Antibodies
    CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))
    Binding Specificity
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 12
    • 12
    • 6
    • 2
    Human
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CNGA3 antibody is un-conjugated
    Application
    • 8
    • 6
    • 4
    • 1
    Western Blotting (WB), ELISA
    Specificity
    CNGA3 Antibody detects endogenous levels of total CNGA3.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human CNGA3, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CNGA3 Primary Antibody
  • Application Notes
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))
    Alternative Name
    CNGA3 (CNGA3 Products)
    Synonyms
    ACHM2 antibody, CCNC1 antibody, CCNCa antibody, CCNCalpha antibody, CNCG3 antibody, CNG3 antibody, CNGA3 antibody, cyclic nucleotide gated channel alpha 3 antibody, CNGA3 antibody, Cnga3 antibody
    Background

    Description: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.

    Gene: CNGA3

    Molecular Weight
    79 kDa
    Gene ID
    1261
    UniProt
    Q16281
    Pathways
    Phototransduction
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