CDK2AP2 antibody (C-Term)

Catalog No. ABIN6260724

Product Details anti-CDK2AP2 Antibody

Target: CDK2AP2 (Cyclin-Dependent Kinase 2 Associated Protein 2 (CDK2AP2))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK2AP2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: CDKA2 Antibody detects endogenous levels of total CDKA2.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CDKA2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CDK2AP2

Target: CDK2AP2 (Cyclin-Dependent Kinase 2 Associated Protein 2 (CDK2AP2))

Alternative Name: CDK2AP2 (CDK2AP2 Products)

Synonyms: DOC-1R antibody, p14 antibody, zgc:92182 antibody, 5830466O21Rik antibody, D19Ertd144e antibody, Doc-1r antibody, cyclin dependent kinase 2 associated protein 2 antibody, cyclin-dependent kinase 2 associated protein 2 antibody, CDK2-associated protein 2 antibody, CDK2AP2 antibody, cdk2ap2 antibody, Cdk2ap2 antibody

Background:

Description: Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes (By similarity). Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation, represses CDK2 activation by inhibiting its interaction with cyclin E and A (PubMed:23781148).

Gene: CDK2AP2

Molecular Weight: 13kDa

Gene ID: 10263

UniProt: O75956

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA