CD46 antibody (N-Term)
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- Target See all CD46 Antibodies
- CD46
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD46 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- CD46 Antibody detects endogenous levels of total CD46.
- Predicted Reactivity
- Sheep
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human CD46, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product CD46 Primary Antibody
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anti-CD46 (CD46) (AA 35-179) antibody
CD46 Reactivity: Human WB, FACS, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 1A5A5 unconjugated
anti-CD46 (CD46) (AA 40-320) antibodyCD46 Reactivity: Human WB, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-CD46 (CD46) (AA 317-343) antibodyCD46 Reactivity: Human WB, FACS, ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 Reactivity: Human, Cow WB, FACS, IP Host: Mouse Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 Reactivity: Human, Cow WB, FACS, IP Host: Mouse Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) (AA 251-355) antibodyCD46 Reactivity: Human, Mouse WB, FACS, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-CD46 (CD46) (AA 317-343), (C-Term) antibodyCD46 Reactivity: Human WB, FACS, IF, IHC (p) Host: Rabbit Polyclonal RB21743 unconjugated
anti-CD46 (CD46) antibodyCD46 Reactivity: Human WB, ELISA, IHC Host: Rabbit Monoclonal 7D12 unconjugated Recombinant Antibody
anti-CD46 (CD46) antibody (FITC)CD46 Reactivity: Human, Cow FACS Host: Mouse Monoclonal MEM-258 FITC
anti-CD46 (CD46) antibody (Biotin)CD46 Reactivity: Human, Cow WB, FACS, IP Host: Mouse Monoclonal MEM-258 Biotin
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- CD46
- Alternative Name
- CD46 (CD46 Products)
- Synonyms
- AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
- Background
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Description: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
Gene: CD46
- Molecular Weight
- 43kDa
- Gene ID
- 4179
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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