CaMK2 beta/gamma antibody

Catalog No. ABIN6260435

Product Details anti-CaMK2 beta/gamma Antibody

Target: CaMK2 beta/gamma

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CaMK2 beta/gamma antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: CaMKIIbeta/gamma Antibody detects endogenous levels of total CaMKIIbeta/gamma

Cross-Reactivity: Human, Mouse (Murine)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CaMKIIbeta/gamma

Isotype: IgG

Application Details

Application Notes: WB 1:1000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for CaMK2 beta/gamma

Target: CaMK2 beta/gamma

Alternative Name: CaMKIIbeta/gamma (CaMK2 beta/gamma Products)

Background:

Description: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

Gene: CAMK2G

Molecular Weight: 62kDa

Gene ID: 818

UniProt: Q13555, Q13554