BPI antibody (Internal Region)

Catalog No. ABIN6260301

Product Details anti-BPI Antibody

Target: BPI (Bactericidal/Permeability Increasing Protein (BPI))

Binding Specificity: Internal Region

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BPI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: BPI Antibody detects endogenous levels of total BPI.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human BPI, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for BPI

Target: BPI (Bactericidal/Permeability Increasing Protein (BPI))

Alternative Name: BPI (BPI Products)

Synonyms: 9230105K17Rik antibody, Bpifd1 antibody, BPIFD1 antibody, rBPI antibody, bpi antibody, bpi.L antibody, lbp antibody, bactericidal/permeability-increasing protein antibody, bactericidal permeablility increasing protein antibody, bactericidal/permeability-increasing protein S homeolog antibody, BPI antibody, Bpi antibody, bpi.S antibody

Background:

Description: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria, this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.

Gene: BPI

Molecular Weight: 54kDa

Gene ID: 671

UniProt: P17213