BCO2 antibody (Internal Region)

Catalog No. ABIN6260239

Product Details anti-BCO2 Antibody

Target: BCO2 (beta-Carotene Oxygenase 2 (BCO2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: BCO2 Antibody detects endogenous levels of total BCO2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human BCO2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for BCO2

Target: BCO2 (beta-Carotene Oxygenase 2 (BCO2))

Alternative Name: BCO2 (BCO2 Products)

Synonyms: BCO2 antibody, bcdo2 antibody, MGC80857 antibody, b-diox-ii antibody, MGC89365 antibody, BCDO2 antibody, DKFZp469E0632 antibody, B-DIOX-II antibody, B-diox-II antibody, Bcdo2 antibody, Bcmo2 antibody, CMO2 antibody, Ab2-079 antibody, beta-carotene oxygenase 2 antibody, beta-carotene oxygenase 2 L homeolog antibody, succinate dehydrogenase complex subunit D antibody, BCO2 antibody, bco2.L antibody, bco2 antibody, SDHD antibody, Bco2 antibody

Background:

Description: Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects.

Gene: BCO2

Molecular Weight: 60-65 kDa

Gene ID: 83875

UniProt: Q9BYV7