ATP1A1 antibody (N-Term)

Catalog No. ABIN6260140

Product Details anti-ATP1A1 Antibody

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: ATP1A1 Antibody detects endogenous levels of total ATP1A1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ATP1A1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

References for anti-ATP1A1 antibody (ABIN6260140)

Wang, Deng, Yue, Chen, Zhang, Shi, Wu: "Glutamine Enhances the Hypoglycemic Effect of Insulin in L6 Cells via Phosphatidylinositol-3-Kinase (PI3K)/Protein Kinase B (AKT)/Glucose Transporter 4 (GLUT4) Signaling Pathway." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 1241-1250, (2018) (PubMed).

Target Details for ATP1A1

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Alternative Name: ATP1A1 (ATP1A1 Products)

Synonyms: Atpa-1 antibody, BC010319 antibody, Nkaa1b antibody, K-ATPase antibody, Na+K+ATPase antibody, atp1a1 antibody, atp1a1a.1 antibody, atp1a1l1 antibody, atp[a]1B1 antibody, cb70 antibody, wu:fa03c03 antibody, wu:fb92h10 antibody, atp1a1l5 antibody, atp[a]1B2 antibody, cb707 antibody, wu:fj34g01 antibody, zgc:92351 antibody, ATPase Na+/K+ transporting subunit alpha 1 antibody, ATPase, Na+/K+ transporting, alpha 1 polypeptide antibody, ATPase Na+/K+ transporting subunit alpha 1 L homeolog antibody, ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 1 antibody, ATPase, Na+/K+ transporting, alpha 1b polypeptide antibody, ATP1A1 antibody, Atp1a1 antibody, atp1a1.L antibody, atp1a1a.1 antibody, atp1a1b antibody

Background:

Description: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Gene: ATP1A1

Molecular Weight: 112kDa

Gene ID: 476

UniProt: P05023

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process