PNPLA2 antibody (Internal Region)

Catalog No. ABIN6260110

Product Details anti-PNPLA2 Antibody

Target: PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNPLA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: PNPLA2 Antibody detects endogenous levels of total PNPLA2.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PNPLA2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PNPLA2

Target: PNPLA2 (Patatin-Like phospholipase Domain Containing 2 (PNPLA2))

Alternative Name: PNPLA2 (PNPLA2 Products)

Synonyms: 1110001C14Rik antibody, ATGL antibody, PEDF-R antibody, TTS-2.2 antibody, TTS2 antibody, iPLA2zeta antibody, PNPLA2 antibody, pnpla2 antibody, 0610039C21Rik antibody, Atgl antibody, RGD1309044 antibody, patatin like phospholipase domain containing 2 antibody, patatin-like phospholipase domain containing 2 antibody, PNPLA2 antibody, pnpla2 antibody, Pnpla2 antibody

Background:

Description: Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674). Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes (PubMed:16239926). May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.

Gene: PNPLA2

Molecular Weight: 54 kDa

Gene ID: 57104

UniProt: Q96AD5