ATG4B antibody (Internal Region)
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- Target See all ATG4B Antibodies
- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ATG4B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- ATG4B Antibody detects endogenous levels of total ATG4B.
- Predicted Reactivity
- Pig,Bovine,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ATG4B, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ATG4B Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
- Alternative Name
- ATG4B (ATG4B Products)
- Synonyms
- apg4b antibody, APG4B antibody, AUTL1 antibody, 2510009N07Rik antibody, AW048066 antibody, Apg4b antibody, Atg4bl antibody, Autl1 antibody, Aut2b2 antibody, autophagy related 4B cysteine peptidase antibody, autophagy-related 4b antibody, Peptidase family C54 protein antibody, cysteine protease ATG4B antibody, ATG4 autophagy related 4 homolog B (S. cerevisiae) antibody, autophagy related 4B, cysteine peptidase antibody, autophagy related 4B, cysteine peptidase L homeolog antibody, ATG4B antibody, Atg4b antibody, AT3G59950 antibody, Tsp_08582 antibody, Tsp_11599 antibody, atg4b antibody, atg4b.L antibody
- Background
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Description: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Gene: ATG4B
- Molecular Weight
- 44kDa
- Gene ID
- 23192
- UniProt
- Q9Y4P1
- Pathways
- Autophagy
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