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PYDC1 antibody

PYDC1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6260072
  • Target See all PYDC1 Antibodies
    PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))
    Reactivity
    • 25
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 28
    • 1
    Rabbit
    Clonality
    • 28
    • 1
    Polyclonal
    Conjugate
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PYDC1 antibody is un-conjugated
    Application
    • 17
    • 15
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    ASC2 Antibody detects endogenous levels of total ASC2
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ASC2
    Isotype
    IgG
  • Application Notes
    WB 1:1000-3000 IHC 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))
    Alternative Name
    ASC2 (PYDC1 Products)
    Synonyms
    ASC2 antibody, POP1 antibody, PYC1 antibody, pyrin domain containing 1 antibody, PYDC1 antibody
    Background

    Description: Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

    Gene: PYDC1

    Molecular Weight
    10 kDa
    Gene ID
    260434
    UniProt
    Q8WXC3
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