APOOL antibody (C-Term)

Catalog No. ABIN6259999

Product Details anti-APOOL Antibody

Target: APOOL (Apolipoprotein O-Like (APOOL))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOOL antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: ApoOL Antibody detects endogenous levels of total ApoOL.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ApoOL, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for APOOL

Target: APOOL (Apolipoprotein O-Like (APOOL))

Alternative Name: APOOL (APOOL Products)

Synonyms: 6720473G16Rik antibody, 9430083G14Rik antibody, E130106L15Rik antibody, CXorf33 antibody, FAM121A antibody, UNQ8193 antibody, RGD1549725 antibody, MGC130618 antibody, APOL antibody, NV11613 antibody, DKFZp459K0210 antibody, apolipoprotein O-like antibody, apolipoprotein O like antibody, apolipoprotein O-like L homeolog antibody, Apool antibody, APOOL antibody, apool.L antibody, apool antibody

Background:

Description: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:23704930), (PubMed:25764979).

Gene: APOOL

Molecular Weight: 30kDa

Gene ID: 139322

UniProt: Q6UXV4