APOC1 antibody (Internal Region)

Catalog No. ABIN6259989

The Rabbit Polyclonal anti-APOC1 antibody has been validated for WB, ICC, ELISA and IF. It is suitable to detect APOC1 in samples from Human.

Quick Overview for APOC1 antibody (Internal Region) (ABIN6259989)

Target: APOC1 (Apolipoprotein C-I (APOC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)

Product Details anti-APOC1 Antibody

Binding Specificity: Internal Region

Specificity: APOC1 Antibody detects endogenous levels of total APOC1.

Predicted Reactivity: Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human APOC1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for APOC1

Target: APOC1 (Apolipoprotein C-I (APOC1))

Alternative Name: APOC1

Background:

Description: Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10 % of the protein of the VLDL and 2 % of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.

Gene: APOC1

Molecular Weight: 9 kDa

Gene ID: 341

UniProt: P02654

Pathways: Apoptosis