APOBR antibody (C-Term)

Catalog No. ABIN6259983

Product Details anti-APOBR Antibody

Target: APOBR (Apolipoprotein B Receptor (APOBR))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOBR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: APOB48R Antibody detects endogenous levels of total APOB48R.

Predicted Reactivity: Pig,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human APOB48R, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for APOBR

Target: APOBR (Apolipoprotein B Receptor (APOBR))

Alternative Name: APOBR (APOBR Products)

Synonyms: APOB48R antibody, Apob-48r antibody, Apob48r antibody, RGD1565169 antibody, APOB100R antibody, apolipoprotein B receptor antibody, apolipoprotein B48 receptor antibody, APOBR antibody, LOC745786 antibody, Apobr antibody

Background:

Description: Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.

Gene: APOBR

Molecular Weight: 115 kDa

Gene ID: 55911

UniProt: Q0VD83