Antizyme Inhibitor 1 antibody (Internal Region)
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- Target See all Antizyme Inhibitor 1 (AZIN1) Antibodies
- Antizyme Inhibitor 1 (AZIN1)
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Binding Specificity
- Internal Region
- Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Antizyme Inhibitor 1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- Antizyme inhibitor 1 Antibody detects endogenous levels of total Antizyme inhibitor 1.
- Predicted Reactivity
- Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Antizyme inhibitor 1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product AZIN1 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- Antizyme Inhibitor 1 (AZIN1)
- Alternative Name
- AZIN1 (AZIN1 Products)
- Synonyms
- OAZI antibody, OAZIN antibody, ODC1L antibody, 1700085L02Rik antibody, AI414949 antibody, Oazi antibody, Oazin antibody, AZIN1 antibody, azin1 antibody, oazin antibody, wu:fj32d12 antibody, MGC81852 antibody, wu:fc93f10 antibody, zgc:110131 antibody, antizyme inhibitor 1 antibody, antizyme inhibitor 1b antibody, antizyme inhibitor 1 L homeolog antibody, antizyme inhibitor 1a antibody, AZIN1 antibody, Azin1 antibody, azin1b antibody, azin1.L antibody, azin1 antibody, azin1a antibody
- Background
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Description: Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240, PubMed:26305948). Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240).
Gene: AZIN1
- Molecular Weight
- 49.5 kDa
- Gene ID
- 51582
- UniProt
- O14977
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