ALDH1A3 antibody (Internal Region)

Catalog No. ABIN6259876

Product Details anti-ALDH1A3 Antibody

Target: ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: ALDH1A3 Antibody detects endogenous levels of total ALDH1A3.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ALDH1A3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ALDH1A3

Target: ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))

Alternative Name: ALDH1A3 (ALDH1A3 Products)

Synonyms: RALDH3 antibody, ALDH1A3 antibody, ALDH1A6 antibody, ALDH6 antibody, MCOP8 antibody, Aldh6 antibody, V1 antibody, aldehyde dehydrogenase 1 family member A3 antibody, aldehyde dehydrogenase 1 family member A3 L homeolog antibody, aldehyde dehydrogenase 1 family, member A3 antibody, aldehyde dehydrogenase family 1, subfamily A3 antibody, ALDH1A3 antibody, aldh1a3.L antibody, aldh1a3 antibody, Aldh1a3 antibody

Background:

Description: NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid (PubMed:27759097). Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde (PubMed:27759097). Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions, retinoic acid is required for normal embryonic development of the eye and the nasal region (By similarity).

Gene: ALDH1A3

Molecular Weight: 56 kDa

Gene ID: 220

UniProt: P47895

Pathways: Retinoic Acid Receptor Signaling Pathway