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ADRM1 antibody (Internal Region)

Adrm1 Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259812
  • Target See all ADRM1 (Adrm1) Antibodies
    ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))
    Binding Specificity
    • 15
    • 14
    • 9
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 57
    • 16
    • 13
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 61
    • 4
    Rabbit
    Clonality
    • 62
    • 3
    Polyclonal
    Conjugate
    • 24
    • 7
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADRM1 antibody is un-conjugated
    Application
    • 33
    • 30
    • 13
    • 13
    • 9
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    ADRM1 Antibody detects endogenous levels of total ADRM1.
    Predicted Reactivity
    Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ADRM1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product Adrm1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))
    Alternative Name
    ADRM1 (Adrm1 Products)
    Synonyms
    arm-1 antibody, gp110 antibody, rpn13 antibody, xoom antibody, ADRM1 antibody, adrm1 antibody, ARM-1 antibody, ARM1 antibody, GP110 antibody, 1110063P18Rik antibody, 2510006J17Rik antibody, AA408205 antibody, AU043535 antibody, Arm1 antibody, Gp110 antibody, Rpn13 antibody, adrm1a antibody, adrm1b antibody, fa12d09 antibody, wu:fa10g10 antibody, wu:fa12d09 antibody, zgc:56107 antibody, zgc:77256 antibody, adhesion regulating molecule 1 antibody, ADRM1 antibody, 19S proteasome regulatory subunit antibody, ADRM1 protein antibody, adrm1 antibody, ADRM1 antibody, CpipJ_CPIJ002929 antibody, SJAG_04211 antibody, Adrm1 antibody
    Background

    Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.

    Gene: ADRM1

    Molecular Weight
    46 kDa
    Gene ID
    11047
    UniProt
    Q16186
    Pathways
    Positive Regulation of Endopeptidase Activity
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