ADAM15 antibody (Internal Region)
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- Target See all ADAM15 Antibodies
- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ADAM15 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- ADAM15 Antibody detects endogenous levels of total ADAM15.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ADAM15, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ADAM15 Primary Antibody
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- Application Notes
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
- Alternative Name
- ADAM15 (ADAM15 Products)
- Synonyms
- ADAM15 antibody, mdc15 antibody, MDC15 antibody, metargidin antibody, tMDCVI antibody, ADAM metallopeptidase domain 15 antibody, ADAM metallopeptidase domain 15 L homeolog antibody, a disintegrin and metallopeptidase domain 15 (metargidin) antibody, ADAM15 antibody, adam15.L antibody, adam15 antibody, Adam15 antibody
- Background
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Description: Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.
Gene: ADAM15
- Molecular Weight
- 93 kDa
- Gene ID
- 8751
- UniProt
- Q13444
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