TADA2L antibody
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- Target See all TADA2L (TADA2A) Antibodies
- TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))
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Reactivity
- Human, Mouse, Rat, Monkey
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TADA2L antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- ADA2L antibody detects endogenous levels of total ADA2L
- Cross-Reactivity
- Human, Monkey, Mouse (Murine), Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ADA2L
- Isotype
- IgG
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anti-Transcriptional Adaptor 2A (TADA2A) (AA 1-305) antibody
TADA2A Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4A8-1A7 unconjugated
anti-Transcriptional Adaptor 2A (TADA2A) (N-Term) antibodyTADA2A Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
anti-Transcriptional Adaptor 2A (TADA2A) (Internal Region) antibodyTADA2A Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Transcriptional Adaptor 2A (TADA2A) (Internal Region) antibodyTADA2A Reactivity: Human, Mouse, Rat, Monkey WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Transcriptional Adaptor 2A (TADA2A) (Internal Region) antibodyTADA2A Reactivity: Human, Mouse, Rat, Monkey, Cow, Rabbit, Dog, Pig WB, IHC, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Transcriptional Adaptor 2A (TADA2A) antibodyTADA2A Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
anti-Transcriptional Adaptor 2A (TADA2A) (AA 338-387) antibodyTADA2A Reactivity: Human, Mouse, Rat, Monkey, Cow, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Bat, Chicken, Hamster WB Host: Rabbit Polyclonal unconjugated
anti-Transcriptional Adaptor 2A (TADA2A) (C-Term) antibodyTADA2A Reactivity: Human, Monkey, Cow, Rabbit, Dog, Guinea Pig, Horse, Bat, Chicken, Hamster WB Host: Rabbit Polyclonal unconjugated
anti-Transcriptional Adaptor 2A (TADA2A) (N-Term) antibodyTADA2A Reactivity: Human, Cow WB Host: Rabbit Polyclonal unconjugated
anti-Transcriptional Adaptor 2A (TADA2A) (AA 1-443) antibodyTADA2A Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500~1:3000, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))
- Alternative Name
- ADA2L (TADA2A Products)
- Background
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Description: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity (PubMed:22644376). May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage (PubMed:22644376).
Gene: TADA2A
- Molecular Weight
- 47kDa
- Gene ID
- 6871
- UniProt
- O75478
- Pathways
- Chromatin Binding
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