Acetyl-CoA Carboxylase beta antibody (N-Term)

Catalog No. ABIN6259711

Product Details anti-Acetyl-CoA Carboxylase beta Antibody

Target: Acetyl-CoA Carboxylase beta (ACACB)

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Acetyl-CoA Carboxylase beta antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: ACACB Antibody detects endogenous levels of total ACACB.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ACACB, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Acetyl-CoA Carboxylase beta

Target: Acetyl-CoA Carboxylase beta (ACACB)

Alternative Name: ACACB (ACACB Products)

Synonyms: F15C21.2 antibody, F15C21_2 antibody, acetyl-CoA carboxylase 2 antibody, ACC2 antibody, ACCB antibody, HACC275 antibody, Acc2 antibody, AI597064 antibody, AW743042 antibody, Accb antibody, acetyl-CoA carboxylase 2 antibody, acetyl-CoA carboxylase beta antibody, acetyl-Coenzyme A carboxylase beta antibody, ACC2 antibody, ACACB antibody, Acacb antibody

Background:

Description: Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in inhibition of fatty acid and glucose oxidation and enhancement of fat storage (By similarity). May play a role in regulation of mitochondrial fatty acid oxidation through malonyl-CoA-dependent inhibition of carnitine palmitoyltransferase 1 (By similarity).

Gene: ACACB

Molecular Weight: 276 kDa

Gene ID: 32

UniProt: O00763

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process