WEE2 antibody
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- Target See all WEE2 Antibodies
- WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
- Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This WEE2 antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- WEE2 Antibody detects endogenous levels of total WEE2
- Cross-Reactivity
- Human, Mouse (Murine)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide
- Isotype
- IgG
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anti-WEE1 Homolog 2 (S. Pombe) (WEE2) (AA 364-393) antibody
WEE2 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-WEE1 Homolog 2 (S. Pombe) (WEE2) (AA 364-393) antibodyWEE2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
- Alternative Name
- WEE2 (WEE2 Products)
- Synonyms
- Xe-wee1 antibody, wee1 antibody, wee1-b antibody, wee1a antibody, wee1b antibody, wee2-b antibody, xwee1 antibody, xwee2 antibody, WEE1B antibody, Gm1065 antibody, Wee1B antibody, WEE2 antibody, im:5913035 antibody, si:ch211-238n5.5 antibody, wu:fi13b10 antibody, zgc:123074 antibody, WEE1 homolog 2 antibody, WEE1 homolog 2 (S. pombe) antibody, wee2 antibody, WEE2 antibody, Wee2 antibody
- Background
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Description: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).
Gene: WEE2
- Molecular Weight
- 60 kDa
- Gene ID
- 494551
- UniProt
- P0C1S8
- Pathways
- M Phase
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