MCF2 antibody (Internal Region)

Catalog No. ABIN6259504

Product Details anti-MCF2 Antibody

Target: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: MCF2 Antibody detects endogenous levels of total MCF2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MCF2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for MCF2

Target: MCF2 (MCF.2 Cell Line Derived Transforming Sequence (MCF2))

Alternative Name: MCF2 (MCF2 Products)

Synonyms: ARHGEF21 antibody, DBL antibody, MCF.2 cell line derived transforming sequence antibody, MCF2 antibody

Background:

Description: Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42.

Gene: MCF2

Molecular Weight: 108 kDa

Gene ID: 4168

UniProt: P10911