ORC1 antibody (Internal Region)

Catalog No. ABIN6259464

Product Details anti-ORC1 Antibody

Target: ORC1 (ORC1L) (Origin Recognition Complex, Subunit 1 (ORC1L))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: ORC1L Antibody detects endogenous levels of total ORC1L.

Predicted Reactivity: Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ORC1L, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ORC1

Target: ORC1 (ORC1L) (Origin Recognition Complex, Subunit 1 (ORC1L))

Alternative Name: ORC1 (ORC1L Products)

Synonyms: CG10667 antibody, DmORC1 antibody, DmOrc1 antibody, DmOrc1p antibody, Dmel\\CG10667 antibody, ORC antibody, ORC1 antibody, dORC1 antibody, orc1 antibody, rDmORC antibody, ORC1L antibody, HSORC1 antibody, PARC1 antibody, orc1l antibody, xorc1 antibody, AA545195 antibody, MmORC1 antibody, Orc1l antibody, Origin recognition complex subunit 1 antibody, origin recognition complex subunit 1 antibody, origin recognition complex subunit 1 L homeolog antibody, origin recognition complex, subunit 1 antibody, Orc1 antibody, ORC1 antibody, orc1.L antibody

Background:

Description: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.

Gene: ORC1

Molecular Weight: 100,120 kDa

Gene ID: 4998

UniProt: Q13415

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA