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PSPC1 antibody (C-Term)

PSPC1 Reactivity: Human, Mouse WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259284
  • Target See all PSPC1 Antibodies
    PSPC1 (Paraspeckle Component 1 (PSPC1))
    Binding Specificity
    • 4
    • 2
    • 2
    • 1
    • 1
    C-Term
    Reactivity
    • 20
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 20
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSPC1 antibody is un-conjugated
    Application
    • 9
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    PSPC1 Antibody detects endogenous levels of total PSPC1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human PSPC1, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PSPC1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    PSPC1 (Paraspeckle Component 1 (PSPC1))
    Alternative Name
    PSPC1 (PSPC1 Products)
    Synonyms
    rexp86 antibody, PSP1 antibody, fj85a06 antibody, wu:fj85a06 antibody, zgc:136470 antibody, 5730470C09Rik antibody, AI327109 antibody, AI449052 antibody, paraspeckle component 1 antibody, paraspeckle component 1 L homeolog antibody, paraspeckle protein 1 antibody, PSPC1 antibody, Tsp_01792 antibody, pspc1 antibody, pspc1.L antibody, Pspc1 antibody
    Background

    Description: Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line (By similarity). Binds to poly(A), poly(G) and poly(U) RNA homopolymers. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Together with NONO, required for the formation of nuclear paraspeckles. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.

    Gene: PSPC1

    Molecular Weight
    58 kDa
    Gene ID
    55269
    UniProt
    Q8WXF1
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