MAEA antibody (Internal Region)

Catalog No. ABIN6259269

Product Details anti-MAEA Antibody

Target: MAEA (Macrophage erythroblast Attacher (MAEA))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAEA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: MAEA Antibody detects endogenous levels of total MAEA.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MAEA, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MAEA

Target: MAEA (Macrophage erythroblast Attacher (MAEA))

Alternative Name: MAEA (MAEA Products)

Synonyms: emp antibody, emlp antibody, pig5 antibody, hlc-10 antibody, MGC81431 antibody, MAEA antibody, MGC64455 antibody, MGC89777 antibody, EMLP antibody, EMP antibody, GID9 antibody, HLC-10 antibody, PIG5 antibody, 1110030D19Rik antibody, Gid9 antibody, wu:fb20a09 antibody, zgc:63708 antibody, macrophage erythroblast attacher S homeolog antibody, macrophage erythroblast attacher antibody, macrophage erythroblast attacher L homeolog antibody, maea.S antibody, MAEA antibody, maea antibody, Maea antibody, maea.L antibody

Background:

Description: Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages, This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.

Gene: MAEA

Molecular Weight: 45 kDa

Gene ID: 10296

UniProt: Q7L5Y9