SLC24A1 antibody (N-Term)

Catalog No. ABIN6259203

Product Details anti-SLC24A1 Antibody

Target: SLC24A1 (Solute Carrier Family 24 (Sodium/potassium/calcium Exchanger), Member 1 (SLC24A1))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC24A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: SLC24A1 Antibody detects endogenous levels of total SLC24A1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SLC24A1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SLC24A1

Target: SLC24A1 (Solute Carrier Family 24 (Sodium/potassium/calcium Exchanger), Member 1 (SLC24A1))

Alternative Name: SLC24A1 (SLC24A1 Products)

Synonyms: SLC24A1 antibody, si:ch211-117i10.3 antibody, CSNB1D antibody, HsT17412 antibody, NCKX antibody, NCKX1 antibody, RODX antibody, Nckx1 antibody, solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 antibody, solute carrier family 24 member 1 antibody, Slc24a1 antibody, SLC24A1 antibody, slc24a1 antibody

Background:

Description: Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca2+ and 1 K+ in exchange for 4 Na+.

Gene: SLC24A1

Molecular Weight: 121 kDa

Gene ID: 9187

UniProt: O60721

Pathways: Phototransduction