RRAGB antibody (Internal Region)
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- Target See all RRAGB Antibodies
- RRAGB (Ras-Related GTP Binding B (RRAGB))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RRAGB antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- RRAGB Antibody detects endogenous levels of total RRAGB.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RRAGB, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product RRAGB Primary Antibody
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- Application Notes
- WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- RRAGB (Ras-Related GTP Binding B (RRAGB))
- Alternative Name
- RRAGB (RRAGB Products)
- Synonyms
- RAGB antibody, bA465E19.1 antibody, Ragb antibody, RRAGB antibody, Ras related GTP binding B antibody, Ras-related GTP binding B antibody, RRAGB antibody, RragB antibody, Rragb antibody
- Background
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Description: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
Gene: RRAGB
- Molecular Weight
- 43 kDa
- Gene ID
- 10325
- UniProt
- Q5VZM2
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