PNPLA6 antibody (Internal Region)

Catalog No. ABIN6259164

Product Details anti-PNPLA6 Antibody

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNPLA6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: PNPLA6 Antibody detects endogenous levels of total PNPLA6.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PNPLA6, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PNPLA6

Target: PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))

Alternative Name: PNPLA6 (PNPLA6 Products)

Synonyms: NTE antibody, NTEMND antibody, SPG39 antibody, iPLA2delta antibody, sws antibody, AI661849 antibody, MSws antibody, Nte antibody, RGD1564611 antibody, wu:fy20f06 antibody, patatin like phospholipase domain containing 6 antibody, patatin-like phospholipase domain containing 6 antibody, PNPLA6 antibody, Pnpla6 antibody, pnpla6 antibody

Background:

Description: Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.

Gene: PNPLA6

Molecular Weight: 150 kDa

Gene ID: 10908

UniProt: Q8IY17

Pathways: Ribonucleoside Biosynthetic Process