PPP1R8 antibody (Internal Region)

Catalog No. ABIN6259156

Product Details anti-PPP1R8 Antibody

Target: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: PPP1R8/ARD1 Antibody detects endogenous levels of total PPP1R8/ARD1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PPP1R8/ARD1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PPP1R8

Target: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Alternative Name: PPP1R8 (PPP1R8 Products)

Synonyms: ARD-1 antibody, ARD1 antibody, NIPP-1 antibody, NIPP1 antibody, PRO2047 antibody, 6330548N22Rik antibody, AU044684 antibody, PPP1R8 antibody, ard-1 antibody, ard1 antibody, nipp-1 antibody, nipp1 antibody, ppp1r8 antibody, si:ch211-206a7.1 antibody, protein phosphatase 1 regulatory subunit 8 antibody, protein phosphatase 1, regulatory subunit 8 antibody, protein phosphatase 1, regulatory (inhibitor) subunit 8 antibody, protein phosphatase 1, regulatory subunit 8b antibody, protein phosphatase 1 regulatory subunit 8 L homeolog antibody, protein phosphatase 1, regulatory subunit 8a antibody, protein phosphatase 1 regulatory subunit 8 S homeolog antibody, PPP1R8 antibody, Ppp1r8 antibody, ppp1r8b antibody, ppp1r8.L antibody, ppp1r8a antibody, ppp1r8.S antibody

Background:

Description: Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.

Gene: PPP1R8

Molecular Weight: 40 kDa

Gene ID: 5511

UniProt: Q12972