nectin-3 antibody (Internal Region)
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- Target See all nectin-3 (NECTIN3) Antibodies
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This nectin-3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- PVRL3 Antibody detects endogenous levels of total PVRL3.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human PVRL3, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product NECTIN3 Primary Antibody
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anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 282-404) antibody
NECTIN3 Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 6D5B2 unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 84-97), (Extracellular), (N-Term) antibodyNECTIN3 Reactivity: Human, Mouse, Rat WB, IHC, FACS, IF Host: Rabbit Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 59-166) antibodyNECTIN3 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 1D1 unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 90-293) antibodyNECTIN3 Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 310-549) antibodyNECTIN3 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 1-366) antibodyNECTIN3 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 171-377) antibodyNECTIN3 Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (Internal Region) antibodyNECTIN3 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (AA 507-536), (C-Term) antibodyNECTIN3 Reactivity: Human WB Host: Rabbit Polyclonal RB32653 unconjugated
anti-Nectin cell adhesion molecule 3 (NECTIN3) (Center) antibodyNECTIN3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- Alternative Name
- NECTIN3 (NECTIN3 Products)
- Background
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Description: Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Gene: NECTIN3
- Molecular Weight
- 61 kDa
- Gene ID
- 25945
- UniProt
- Q9NQS3
- Pathways
- Cell-Cell Junction Organization
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