NOC2L antibody (C-Term)
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- Target See all NOC2L Antibodies
- NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NOC2L antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- NOC2L Antibody detects endogenous levels of total NOC2L.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human NOC2L, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product NOC2L Primary Antibody
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anti-Nucleolar Complex Associated 2 Homolog (NOC2L) antibody
NOC2L Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- NOC2L (Nucleolar Complex Associated 2 Homolog (NOC2L))
- Alternative Name
- NOC2L (NOC2L Products)
- Synonyms
- NET15 antibody, NET7 antibody, NIR antibody, AA410003 antibody, AF155546 antibody, RGD1309387 antibody, NOC2 like nucleolar associated transcriptional repressor antibody, NOC2-like nucleolar associated transcriptional repressor antibody, NOC2L antibody, Noc2l antibody
- Background
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Description: Acts as an inhibitor of histone acetyltransferase activity, prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter.
Gene: NOC2L
- Molecular Weight
- 85 kDa
- Gene ID
- 26155
- UniProt
- Q9Y3T9
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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