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NK2 Homeobox 5 antibody (Internal Region)

NKX2-5 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259127
  • Target See all NK2 Homeobox 5 (NKX2-5) Antibodies
    NK2 Homeobox 5 (NKX2-5)
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 40
    • 19
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 42
    • 7
    • 1
    Rabbit
    Clonality
    • 44
    • 6
    Polyclonal
    Conjugate
    • 36
    • 4
    • 3
    • 3
    • 2
    • 2
    This NK2 Homeobox 5 antibody is un-conjugated
    Application
    • 42
    • 29
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Nkx2.5 Antibody detects endogenous levels of total Nkx2.5.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Nkx2.5, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product NKX2-5 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    NK2 Homeobox 5 (NKX2-5)
    Alternative Name
    NKX2-5 (NKX2-5 Products)
    Synonyms
    CHNG5 antibody, CSX antibody, CSX1 antibody, HLHS2 antibody, NKX2.5 antibody, NKX2E antibody, NKX4-1 antibody, VSD3 antibody, Csx antibody, Nkx-2.5 antibody, Nkx2.5 antibody, tinman antibody, nk2.5 antibody, nkx2-5 antibody, zgc:111912 antibody, AR2 antibody, XNkx2-5 antibody, csx antibody, nkx-2.5 antibody, nkx2-5b antibody, nkx2.5 antibody, NKX2-5 antibody, Nkx2-5 antibody, csx1 antibody, nkx2e antibody, XNkx-2.5 antibody, CNKX-2.5 antibody, NKX-2.5 antibody, NK2 homeobox 5 antibody, NK2 homeobox 5 S homeolog antibody, NKX2-5 antibody, Nkx2-5 antibody, nkx2.5 antibody, nkx2-5.S antibody, nkx2-5 antibody
    Background

    Description: Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). Binds to the core DNA motif of NPPA promoter (PubMed:22849347, PubMed:26926761). It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development.

    Gene: NKX2-5

    Molecular Weight
    50 kDa
    Gene ID
    1482
    UniProt
    P52952
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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