MORG1 antibody (Internal Region)

Catalog No. ABIN6259117

Product Details anti-MORG1 Antibody

Target: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MORG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: MORG1 Antibody detects endogenous levels of total MORG1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MORG1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for MORG1

Target: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Alternative Name: WDR83 (wdr83 Products)

Synonyms: MORG1 antibody, 1500041N16Rik antibody, Morg1 antibody, RGD1306947 antibody, morg1 antibody, MAPK organizer 1 antibody, wu:fj29g04 antibody, zgc:92654 antibody, WD repeat domain 83 antibody, WD repeat domain containing 83 antibody, WD repeat domain 83 L homeolog antibody, WDR83 antibody, Wdr83 antibody, wdr83.L antibody, wdr83 antibody

Background:

Description: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.

Gene: WDR83

Molecular Weight: 34 kDa

Gene ID: 84292

UniProt: Q9BRX9