Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MSH3 antibody (N-Term)

MSH3 Reactivity: Human WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259074
  • Target See all MSH3 Antibodies
    MSH3 (MutS Homolog 3 (MSH3))
    Binding Specificity
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 33
    • 3
    • 2
    Human
    Host
    • 33
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MSH3 antibody is un-conjugated
    Application
    • 13
    • 13
    • 11
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    MSH3 Antibody detects endogenous levels of total MSH3.
    Predicted Reactivity
    Pig,Horse,Sheep,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MSH3, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MSH3 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    MSH3 (MutS Homolog 3 (MSH3))
    Alternative Name
    MSH3 (MSH3 Products)
    Synonyms
    ATMSH3 antibody, M7J2.90 antibody, M7J2_90 antibody, homolog of DNA mismatch repair protein MSH3 antibody, DUP antibody, MRP1 antibody, D13Em1 antibody, Rep-3 antibody, Rep3 antibody, mutS homolog 3 antibody, DNA mismatch repair protein MSH3 antibody, homolog of DNA mismatch repair protein MSH3 antibody, mismatch repair protein antibody, MSH3 antibody, Msh3 antibody
    Background

    Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

    Gene: MSH3

    Molecular Weight
    127 kDa
    Gene ID
    4437
    UniProt
    P20585
    Pathways
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
You are here:
Support