RAB3GAP1 antibody (Internal Region)

Catalog No. ABIN6259056

Product Details anti-RAB3GAP1 Antibody

Target: RAB3GAP1 (RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB3GAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: RAB3GAP1 Antibody detects endogenous levels of total RAB3GAP1.

Predicted Reactivity: Horse,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RAB3GAP1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for RAB3GAP1

Target: RAB3GAP1 (RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1))

Alternative Name: RAB3GAP1 (RAB3GAP1 Products)

Synonyms: 1700003B17Rik antibody, 4732493F09Rik antibody, AL117896 antibody, Rab3gap antibody, p130 antibody, P130 antibody, RAB3GAP antibody, RAB3GAP130 antibody, WARBM1 antibody, RAB3 GTPase activating protein subunit 1 antibody, RAB3 GTPase activating protein catalytic subunit 1 antibody, Rab3gap1 antibody, RAB3GAP1 antibody

Background:

Description: Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

Gene: RAB3GAP1

Molecular Weight: 117 kDa

Gene ID: 22930

UniProt: Q15042