CHSY1 antibody (Internal Region)

Catalog No. ABIN6259032

Product Details anti-CHSY1 Antibody

Target: CHSY1 (Chondroitin Sulfate Synthase 1 (CHSY1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHSY1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: CHSY1 Antibody detects endogenous levels of total CHSY1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CHSY1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CHSY1

Target: CHSY1 (Chondroitin Sulfate Synthase 1 (CHSY1))

Alternative Name: CHSY1 (CHSY1 Products)

Synonyms: mKIAA0990 antibody, CHSY antibody, CSS1 antibody, ChSy-1 antibody, TPBS antibody, chys1 antibody, wu:fc27h05 antibody, wu:fc27h06 antibody, zgc:64191 antibody, chondroitin sulfate synthase 1 antibody, Chsy1 antibody, CHSY1 antibody, chsy1 antibody

Background:

Description: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.

Gene: CHSY1

Molecular Weight: 91 kDa

Gene ID: 22856

UniProt: Q86X52

Pathways: Glycosaminoglycan Metabolic Process