GPR114 antibody (Internal Region)

Catalog No. ABIN6258942

Product Details anti-GPR114 Antibody

Target: GPR114 (G Protein-Coupled Receptor 114 (GPR114))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR114 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: GPR114 Antibody detects endogenous levels of total GPR114.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GPR114, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GPR114

Target: GPR114 (G Protein-Coupled Receptor 114 (GPR114))

Alternative Name: ADGRG5 (GPR114 Products)

Synonyms: PGR27 antibody, Gm1109 antibody, adhesion G protein-coupled receptor G5 antibody, ADGRG5 antibody, Adgrg5 antibody

Background:

Description: Adhesion G protein-coupled receptor (GPCR). Transduces intracellular signals through coupling to guanine nucleotide-binding protein G(s) subunit alpha and activation of adenylate cyclase pathway. Isoform 1, but not isoform 2, is constitutively active, as evidenced by elevated basal cAMP levels, and responds to mechanical activation (shaking).

Gene: ADGRG5

Molecular Weight: 59 kDa

Gene ID: 221188

UniProt: Q8IZF4