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Manic Fringe antibody (Internal Region)

Name: Manic Fringe antibody (Internal Region)
SKU: ABIN6258883
Price: 390.77 USD
Availability: InStock

MFNG Reactivity: Human, Mouse, Rat WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated

Western blot analysis of extracts from HepG2 cells, using MFNG antibody. (Manic Fringe antibody (Internal Region))

IF/ICC

2 images

Catalog No. ABIN6258883

Datasheet as PDF

Target See all Manic Fringe (MFNG) Antibodies

Manic Fringe (MFNG) (MFNG)
Binding Specificity
16

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1
Internal Region
Reactivity
27

25

9

5

5

4

4

4

2

2

2

2

1

1
Human, Mouse, Rat
Host
40

4

1
Rabbit
Compatible Secondaries
Clonality
44

1
Polyclonal
Conjugate
21

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Manic Fringe antibody is un-conjugated
Application
19

14

13

13

13

6

5

4

3

1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity

MFNG Antibody detects endogenous levels of total MFNG.

Predicted Reactivity

Pig,Bovine,Horse,Dog

Purification

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen

A synthesized peptide derived from human MFNG, corresponding to a region within the internal amino acids.

Isotype

IgG
anti-MFNG (MFNG) (AA 214-291) antibody
MFNG Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated

anti-MFNG (MFNG) (C-Term) antibody
MFNG Reactivity: Human, Dog, Horse, Rabbit, Guinea Pig, Bat WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-MFNG (MFNG) (AA 56-309) antibody
MFNG Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-MFNG (MFNG) antibody
MFNG Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

anti-MFNG (MFNG) (AA 28-321) antibody
MFNG Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-MFNG (MFNG) (AA 221-321) antibody
MFNG Reactivity: Mouse ELISA, FACS, IF (p), IF (cc), ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-MFNG (MFNG) (AA 214-291) antibody
MFNG Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2B11 unconjugated

anti-MFNG (MFNG) (AA 1-321) antibody
MFNG Reactivity: Human WB Host: Mouse Polyclonal unconjugated

anti-MFNG (MFNG) (AA 241-290) antibody
MFNG Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio), Pig, Monkey, Chicken, Hamster WB Host: Rabbit Polyclonal unconjugated

anti-MFNG (MFNG) (AA 211-260) antibody
MFNG Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Bat, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date

12 months
Target

Manic Fringe (MFNG) (MFNG)

Alternative Name

MFNG (MFNG Products)

Synonyms

AW546563 antibody, MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antibody, MFNG antibody, Mfng antibody

Background

Description: Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626). Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity).
Gene: MFNG

Molecular Weight

38 kDa

Gene ID

4242

UniProt

O00587

Pathways

Notch Signaling