HCRTR1 antibody (C-Term)

Catalog No. ABIN6258840

Product Details anti-HCRTR1 Antibody

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCRTR1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: HCRTR1 Antibody detects endogenous levels of total HCRTR1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HCRTR1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for HCRTR1

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Alternative Name: HCRTR1 (HCRTR1 Products)

Synonyms: OX1R antibody, Ox1r antibody, Hctr1 antibody, HCRTR1 antibody, hypocretin receptor 1 antibody, hypocretin (orexin) receptor 1 antibody, HCRTR1 antibody, Hcrtr1 antibody

Background:

Description: Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca2+ levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).

Gene: HCRTR1

Molecular Weight: 50 kDa

Gene ID: 3061

UniProt: O43613

Pathways: Feeding Behaviour