ELOVL6 antibody (N-Term)

Catalog No. ABIN6258769

Product Details anti-ELOVL6 Antibody

Target: ELOVL6 (ELOVL Fatty Acid Elongase 6 (ELOVL6))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELOVL6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: ELOVL6 Antibody detects endogenous levels of total ELOVL6.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ELOVL6, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ELOVL6

Target: ELOVL6 (ELOVL Fatty Acid Elongase 6 (ELOVL6))

Alternative Name: ELOVL6 (ELOVL6 Products)

Synonyms: FACE antibody, FAE antibody, LCE antibody, C77826 antibody, Lce2 antibody, rELO2 antibody, lce antibody, cb618 antibody, zgc:73089 antibody, elovl6 antibody, ELOVL fatty acid elongase 6 antibody, ELOVL family member 6, elongation of long chain fatty acids (yeast) antibody, elongation of very long chain fatty acids protein 6 antibody, elongation of very long chain fatty acids protein 6-like antibody, ELOVL6 antibody, Elovl6 antibody, elovl6 antibody, Tsp_06132 antibody, LOC108710167 antibody

Background:

Description: Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

Gene: ELOVL6

Molecular Weight: 35 kDa

Gene ID: 79071

UniProt: Q9H5J4